1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity connected with bortezomib, a proteasome inhibitor Utilized in the cure of a number of myeloma. Its synthesis or examine is essential for making sure the purity and basic safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets distinct varieties of most cancers, like Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers which include breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is crucial for optimizing the manufacturing system and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is employed to deal with breast (7a most cancers, and these intermediates are involved in its manufacturing.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Employed in the therapy of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in treating cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and little mobile GeMcitabine Intermediate 8 lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, which have a variety of apps, together with antiviral properties.
Vildagliptin Intermediates: Employed in the manufacture of vildagliptin, an oral drug for form 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor during the synthesis of canagliflozin, a medication used to manage kind 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).